Atoms or systems into ruin hurl’d, And now a bubble burst, and now a world. And if the asteroids don’t get us, there’s always the chance that an alternate universe might pop and destroy everything, a la Richard Grant in How to Get Ahead in Advertising. “The problem, says Lykken, is the potential for vacuum instability — a phenomenon that could spawn an all-consuming alternate universe within our own.”
Not as pressing as asteroids, however — this event, if current calculations hold up, is most likely to happen round the End of the Universe anyway, so be sure to get a table by the window.