Good News, Coffee Achievers.

“In one large-scale epidemiological study from last year, researchers primarily at the National Cancer Institute parsed health information from more than 400,000 volunteers, ages 50 to 71, who were free of major diseases at the study’s start in 1995…men who reported drinking two or three cups of coffee a day were 10 percent less likely to have died than those who didn’t drink coffee, while women drinking the same amount had 13 percent less risk of dying during the study.”

Better living through chemistry: The NYT’s Gretchen Reynolds touts the potential medical benefits of caffeine addiction. “Participants with little or no caffeine circulating in their bloodstreams were far more likely to have progressed to full-blown Alzheimer’s than those whose blood indicated they’d had about three cups’ worth of caffeine.” Factor in all the taurine I consume to boot, and I’m disco.

Seven Minutes of Fury.

“In 12 exercises deploying only body weight, a chair and a wall, it fulfills the latest mandates for high-intensity effort…into about seven minutes of steady discomfort — all of it based on science.”

To complement Calvinism: The NYT lays out a seven-minute workout that might actually work. “The exercises should be performed in rapid succession, allowing 30 seconds for each, while, throughout, the intensity hovers at about an 8 on a discomfort scale of 1 to 10…Those seven minutes should be, in a word, unpleasant.”

The Pleasures of the Void.

“I slid the blackout door closed behind me, eased down into the water, and touched a button that switched off the lights. I was floating in total darkness and silence…For what must have been the first 15 minutes, I wondered what I was doing there…Then a transformation began…My brain went a little haywire. When the storm passed, I found myself in a new and unfamiliar state of mind.”

To kick off his new Slate column “Anything Once,” friend Seth Stevenson finds himself reveling in the sensation of sensory deprivation. “I emerged in a profound daze. I spoke slowly and quietly, like a smooth-jazz DJ, to the person at the spa desk who inquired how my session had gone. I felt more rested than if I’d slept for 16 hours on a pile of tranquilized chinchillas. Outside, colors were saturated; sounds were vivid. I had to try this again, as soon as possible.”

Follow the Bouncing Dot.

“‘We are trying to understand how human motor performance changes with age,’ the researchers say. ‘We believe that research should be done in collaboration with people—with people like you who are interested in learning about themselves and helping research.'”

An online Harvard experiment tries to guess your age by evaluating your mouse-clicking ability. Hard to say how good it is, really. It deemed me thirty — eight years too young — but then again, with blogging and gaming both ranking high among the extra-curriculars, I probably use a mouse more than most people too.

The Expanding Nation.

“This shows the percentages of the U.S. population medically defined as obese, which means a body mass index of 30 or greater…By now everyone knows obesity is a serious issue, but it always helps me to see things moving and in color, and makes the ‘epidemic’ terminology make sense.

A troubling GIF captures twenty-five years of expanding waistlines in America. “Meanwhile, through 2012, no state has met the CDC’s nationwide goal to reduce obesity to 15 percent.” Update: The states behind the curve? Everyone could be lying.

Don’t Sleep on Second Sleep.

“In 2001, historian Roger Ekirch of Virginia Tech published a seminal paper, drawn from 16 years of research, revealing a wealth of historical evidence that humans used to sleep in two distinct chunks…Today, most people seem to have adapted quite well to the eight-hour sleep, but Ekirch believes many sleeping problems may have roots in the human body’s natural preference for segmented sleep as well as the ubiquity of artificial light.”

When you’re lying awake at night, it’s alright: BBC’s Stephanie Hegarty delves into pre-industrial sleep habits and discovers that eight hours of uninterrupted sleep may be a recent invention. “Much like the experience of Wehr’s subjects, these references describe a first sleep which began about two hours after dusk, followed by waking period of one or two hours and then a second sleep. ‘It’s not just the number of references – it is the way they refer to it, as if it was common knowledge,’ Ekirch says.”

Better Living through Virology.

“[Above] is a look at the past morbidity (how many people became sick) of what were once very common infectious diseases, and the current morbidity in the U.S. There’s no smallpox and no polio, almost no measles, dramatically less chickenpox (also known as varicella) and H. influenza (that’s not flu, but a bacteria that can cause deadly meningitis.” How Vaccines Have Changed Our World in One Graphic.

Braaaaaiiiiiiiiiins.

“‘Every dollar we invested to map the human genome returned $140 to our economy — every dollar,’ he said. ‘Today our scientists are mapping the human brain to unlock the answers to Alzheimer’s. They’re developing drugs to regenerate damaged organs, devising new materials to make batteries 10 times more powerful. Now is not the time to gut these job-creating investments in science and innovation.'”

President Obama makes the case for federal investment in the Brain Activity Map Project. (You heard it here first, tinfoil hat people. The tyranny of the Kenyan socialist will not stop at your precious bodily fluids — He’s going to read your brainwaves too!) Seriously, though, investing in basic scientific research like this is, er, a no-brainer. It creates jobs while advancing the frontiers of human knowledge in all kinds of unanticipated ways. We’d be stupid not to support this — which means, of course, the jury’s still out on whether we will.

Update: “BAM is an acronym you’ll probably be hearing a lot in the weeks and months to come — so let’s talk about what the BAM project is, what it isn’t, and why it’s raising both interest and eyebrows throughout the scientific community.” Io9 has more.

I feel worse already.

‘The work shows that processes like placebo and nocebo happen without us being aware of the cues that trigger them,’ said Jensen. ‘We get these responses due to associative learning. We don’t need somebody standing there saying ‘ok, now you will feel less pain’. It’s being elicited naturally, and without us being aware, all the time.’

A new study finds that subliminal cues help create the placebo effect (and its opposite, the “nocebo effect”)…although, reading the overview of the experiment here, the conclusion sounds more like: People will subliminally recoil from bad things that happen to them.

Rolling the Clocks Back.

[T]his new method changes everything. To start with, it uses normal adult blood cells from the patient, so there’s not need to keep umbilical cords in storage. It also doesn’t use any virus reprogramming, so it’s completely safe. It’s also very efficient: researchers successfully transformed about 50 to 60 percent of adult blood cells into embryonic stem cells that can then be turn into any type of cell—a heart muscle cell, a bone cell, a nerve cell, anything.

By way of Dangerous Meta, researchers figure out a way to manufacture embryonic stem cells without an embryo, thus clearing the path for future research in that direction unhampered by abortion politics. “The discovery could be the key to cure the incurable – from heart attacks to severed spinal cord to cancer—and open the door, some day, to eternal youth.